Basic and Clinical Pharmacology 12th Edition, by Bertram Katzung, Susan Masters and Anthony Trevor describe the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors’ many years experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.
To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations, this book features numerous summary tables and diagrams that encapsulate important information.
Coverage that spans every aspect of medical pharmacology basic principles, autonomic drugs, cardiovascular-renal drugs, drugs with important actions on smooth muscles, central nervous system drugs, drugs used to treat anemias, clotting disorders, hyperlipidemia, and inflammation and gout, endocrine drugs, chemotherapeutic and immunologic drugs, toxicology, special subjects (perinatal, geriatric, and dermatologic pharmacology), botanical and "food supplements," and over-the-counter medications.
Drug Summary Tables conclude most chapters, providing a concise summary of the most important drugs. There are general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters with descriptions of important new drugs, including monoclonal antibodies. The book also offers special features that make it a useful reference for house officers and practicing clinicians.
Information is organized according to the sequence used in many pharmacology courses and in integrated curricula: basic principles; autonomic drugs; cardiovascular-renal drugs; drugs with important actions on smooth muscle; central nervous system drugs; drugs used to treat inflammation, gout, and diseases of the blood; endocrine drugs; chemotherapeutic drugs; toxicology; and special topics. This sequence builds new information on a foundation of information already assimilated.
For example, early presentation of autonomic nervous system pharmacology allows students to integrate the physiology and neuroscience they have learned elsewhere with the pharmacology they are learning and prepares them to understand the autonomic effects of other drugs. This is especially important for the cardiovascular and central nervous system drug groups. However, chapters can be used equally well in courses and curricula that present these topics in a different sequence.
Within each chapter, emphasis is placed on discussion of drug groups and prototypes rather than offering repetitive detail about individual drugs. Selection of the subject matter and the order of its presentation are based on the accumulated experience of teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.
Major features that make this book particularly useful in integrated curricula include sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects—in other words, clinical pharmacology is an integral part of this text. Lists of the commercial preparations available, including trade and generic names and dosage formulations, are provided at the end of each chapter for easy reference by the house officer or practitioner writing a chart order or prescription.
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