Pharmacology: A Nursing Process Approach 7th Edition

Pharmacology: A Nursing Process Approach 7th Edition, by Joyce LeFever Kee, Evelyn R. Hayes and Linda E. McCuistion offers concise, straightforward coverage by putting nursing pharmacology concepts and essential drug calculation skills into a practical nursing context to prepare you for real-world drug administration responsibilities.

This edition has been revised and updated with the most current nursing pharmacology information available. Innovative features such as Prototype Drug Charts, Nursing Process Summaries, an extensive math/dosage calculation section, and NCLEX® Examination-style study questions make nursing pharmacology more understandable than ever.

Prototype Drug Charts provide easy access to key information on dosages, contraindications, drug-lab-food interactions, pharmacokinetics, and more for more than 100 drugs. An extensive, color-coded dosage calculation section covers six methods of dosage calculation - basic formula, ratio and proportion, fractional equation, dimensional analysis, and dosing by body weight and body surface area - eliminating the need for a separate dosage calculation book.

Nursing Process Summaries present client care and drug therapy within the framework of each step of the nursing process, including information on client teaching and cultural and herbal considerations. Preventing Medication Errors boxes reinforce concepts introduced in the medication safety chapter and highlight common errors that occur in clinical practice to help you ensure safe drug administration.

Herbal Alerts provide a quick reference to side effects, drug interactions, and additional information for popular herbs you may encounter in practice. A fully updated bioterrorism appendix helps you recognize the clinical manifestations of bioterrorism weapons and respond with appropriate nursing care. Illustrated overviews of normal anatomy and physiology in all drug therapy chapters help you understand how drugs work in various body systems.

Critical Thinking Case Studies at the end of each chapter challenge you to apply your knowledge and analytical skills to realistic client scenarios. NCLEX® Study Questions for each chapter help prepare you for the growing pharmacology coverage on the NCLEX® Examination. Answers are listed upside-down at the bottom of the page for quick feedback.

New medication safety chapter discusses medication errors, specific nursing measures to prevent medication errors, possible consequences of medication errors to nurses, responses to errors, reporting and learning from mistakes, and related ethical issues. Enhanced NCLEX® Examination-style study questions are now more application-based and include at least one alternate-item format question per chapter.

Updated chapters on cultural considerations and women's health bring you the latest information on these important considerations in drug therapy. More reader-friendly and understandable than ever, this edition features helpful new photos throughout.

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Calculate with Confidence 5th Edition, Deborah Gray Morris

Calculate with Confidence 5th Edition by Deborah Gray Morris provides a clear consistent format with a step-by-step approach to the calculation and administration of drug dosages. It covers the ratio and proportion, formula, and dimensional analysis methods. This popular text focuses on enhancing the learning experience of student at all curricular levels by making content clinically applicable.

Concepts relating to critical thinking, logical thinking, and nursing process are presented throughout. New practice problems have been added throughout this edition and rationales for the answers continue to be provided giving the students a better understanding of principles related to drug dosages.

This book addresses the increasing responsibility of nurses in medication and administration; emphasizes the priority for client care, and presents material that reflects the current scope of the nursing practice. A clear and consistent, step-by-step approach to calculations and administration makes it easy to understand.

Ratio and Proportion, Formula, and Dimensional Analysis content provides you with well-rounded coverage .Pretest and post-test help identify strengths and weaknesses in competency of basic math before and assess your comprehension after Unit One: Math Review. “Points to Remember” boxes highlighted in each chapter help you remember important concepts.

Critical thinking information that should be applied in the clinical setting to help avoid drug calculation and administration errors is boxed throughout the text. Full-color illustrations, photographs, and drug labels familiarize you with what you'll encounter in the clinical setting. Current recommendations from The Joint Commission and Institute for Safe Medication Practices are followed throughout.

Caution boxes identify issues that may lead to medication errors and strengthen actions that must be taken to avoid calculation errors. Tips for Clinical Practice calls attention to information critical to math calculation and patient safety as well as issues related to practice. Rule boxes familiarize students with information needed to accurately solve drug calculation problems.

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Group Sequential Methods with Applications to Clinical Trials

Group Sequential Methods with Applications to Clinical Trials by Christopher Jennison and Bruce W. Turnbull presents a comprehensive presentation of group sequential methods. Written by active researchers in this area, it provides an ideal source for those wishing an introduction to the area and for those who desire a clear outline of specific topics or methods.

Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion.

This text describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models.

Research in group sequential analysis has progressed rapidly over the past 20 years. This text surveys and extends current methods for planning and conducting interim analyses. It provides straightforward descriptions of group sequential hypothesis tests in a form suited for direct application to a wide variety of clinical trials. Medical statisticians engaged in any investigations planned with interim analyses will find this book a useful and important tool.

It should quickly become a standard reference both for those wishing to apply the methods and for researchers in the area. The extent of coverage of various topics broadly reflects current usage. The discussion of each topic appears to be well balanced. All in all, this is a very welcome book. The statistical methodology for sequential trials is complicated.

This book provides an excellent presentation of it. It succeeds as both a training text and as a reference source. I liked the progression of the book. Any statistician involved in designing or analyzing sequential trials should have a copy.

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Drug Design: Structure- and Ligand-Based Approaches

Drug Design: Structure- and Ligand-Based Approaches by Kenneth M. Merz, Dagmar Ringe and Charles H. Reynolds provides a complete snapshot of the field of computer-aided drug design and associated experimental approaches. Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and commercial realms.

Methods utilized in computer-aided drug design can be classified into two major categories: structure based and ligand based, using information on the structure of the protein or on the biological and physicochemical properties of bound ligands, respectively. In recent years there has been a trend towards integrating these two methods in order to enhance the reliability and efficiency of computer-aided drug-design approaches by combining information from both the ligand and the protein.

Topics covered include X-ray crystallography, NMR, fragment-based drug design, free energy methods, docking and scoring, linear-scaling quantum calculations, QSAR, pharmacophore methods, computational ADME-Tox, and drug discovery case studies. A variety of authors from academic and commercial institutions all over the world have contributed to this book, which is illustrated with more than 200 images.

Authors also describe pseudoreceptor methods, pharmacophore methods, fingerprint methods and approaches integrating docking with similarity-based methods. In this article, we will describe the concepts behind each method and selected applications.

This is the only book to cover the subject of structure and ligand-based drug design, and it provides the most up-to-date information on a wide range of topics for the practicing computational chemist, medicinal chemist, or structural biologist.

Kenneth M. Merz received his PhD in organic chemistry at the University of Texas at Austin and completed postdoctoral research at Cornell University and the University of California, San Francisco. He is a member of the Quantum Theory Project and Professor of Chemistry at the University of Florida, Gainesville.

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Analytical Chemistry in a GMP Environment: A Practical Guide

Analytical Chemistry in a GMP Environment: A Practical Guide by Jim Miller, James M. Miller and Jonathan B. Crowther provides guidance for laboratory analysts who must juggle the Food and Drug Administration's good manufacturing practices (GMP) rules with rapidly changing analytical technologies.

Highly qualified industry experts walk readers step-by-step through the concepts, techniques, and tools necessary to perform analyses in an FDA-regulated environment, including clear instructions on all major analytical chemical methods-from spectroscopy to chromatography to dissolution. This text shows how to hone your analytical skills and obtain high-quality data in the era of GMP requirements.

With increased regulatory pressures on the pharmaceutical industry, there is a growing need for capable analysts who can ensure appropriate scientific practices in laboratories and manufacturing sites worldwide. An ideal manual for formal training as well as an excellent self-study guide, this book features the drug development process in the pharmaceutical industry, uniform and consistent interpretation of GMP compliance issues, review of the role of statistics and basic topics in analytical chemistry and emphasis on high-performance liquid chromatographic (HPLC) methods.

There are chapters on detectors and quantitative analysis as well as data systems, methods for ensuring that instruments meet standard operating procedures (SOP) requirements and extensive appendixes for unifying terms, symbols, and procedural information. I recommend this book for anyone who recognizes a need for more and better training of pharmaceutical laboratory analysts.

This text provides a much needed perspective on the role of analytical chemistry in the pharmaceutical industry and is a welcome addition. The book focuses on technical and practical aspects faced by chemists working in the analytical lab. The book is written with an approach to achieve GMP compliance. All chapters have been written by area experts making it very useful and comprehensive.

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